Immunosuppressive Agents Enhance the Cytokine-lnduced Priming of Inflammatory Cells
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چکیده
منابع مشابه
Development and use a Novel Combined In-vivo and In-vitro Assay for Anti-inflammatory and Immunosuppressive Agents
Contact hypersensitivity (CHS) mouse model induced by 2, 4-dinitrofluorobenzene (DNFB) is thought to be a T helper 1 (Th1)-dominant response and used for investigating anti-inflammatory and immunosuppressive agents. However, it is hardly used for screening large-scale drugs because of the large number of animals and complex mechanisms involved in-vivo. In this study, we focused on whether T lym...
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Atherosclerosis is a chronic inflammatory disease caused by dyslipidemia and mediated by both innate and adaptive immune responses. Inflammation is a critical factor at all stages of atherosclerosis progression. Proinflammatory cytokines accelerate atherosclerosis progression, while anti-inflammatory cytokines ameliorate the disease. Accordingly, strategies to inhibit immune activation and impe...
متن کاملPharmacological immunosuppressive agents.
A vast range of different compounds seem capable of depressing the immune response, however, it has been disappointing that so few of these have shown potential as immunosuppressive agents in man. The action of many has been to suppress lymphocyte reactivity in vitro and of those that are capable of prolonging graft survival in animals in addition, just a handful have been found to be safe and ...
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Immunosupressants are drugs that act in cell division and have anti-inflammatory effects. Therefore, they are essentially prescribed in the prevention of transplant rejection and in the treatment of autoimmune disorders and chronic inflammatory diseases, whose main example in Dermatology is psoriasis. In this work the most important immunosuppressive drugs and orientation to properly administer...
متن کاملDifferences among immunosuppressive agents.
Immunosuppressive agents have diverse (although often multiple) sites of action in the cell sequences that are involved in immune responses. New routes to selectivity are apparent at both the cellular and the biochemical level. Meanwhile, clinical work is finding new uses and more selective employment of the currently available agents.
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ژورنال
عنوان ژورنال: International Archives of Allergy and Immunology
سال: 1995
ISSN: 1018-2438,1423-0097
DOI: 10.1159/000236996